Orthopaedic

ORTHOPEADICS

There are many Situations exist where current conventional treatments including surgery have not worked very well and biological treatment has proved to be very promising.

How it works

1.Therapeutic Angiogenesis:

Necessary for delivery of nutrients & oxygen required for Regeneration.

2.Tissue Rejuvenation:

Growth factors secreted by cells Modulate the LocoregionalMilieun

Promote self-repair of residing tissue cells

Activate the dormant local regenerative cells of damaged tissue.

3.Differentiation:

These cells are themselves a rich source of progenitor cells

Differentiate in bone or cartilage under optimum conditions

How it is done

Patients are evaluated clinically, radio logically by XRAY, CT or MRI scans

Patients advised to strictly avoid smoking, drug or alcohol consumption and have a positive life style

As a day care procedure 120 ml of Bone marrow and 100 ml of fat is aspirated and processed for stem cells isolation. 2 ml of stem cells processed as per GMP is injected directly

The procedure is very simple as Intraarticular or Intralesional administration of cells can be done to target site directly under ultrasound guided or C-ARM fluoroscopic control easily.

OSTEOARTHRITIS OF KNEE:

WOMAC values (subsets and total) showed significant improvement from baseline over the course of six months treatment (p < 0.001).
The pain free distance covered during a Six-minute walk (6MWD) also significantly improved by 140 feet ((p<.001).
Requirement of rescue medication decreased to once a week in 45%.
The mean (SD) change for the percentage of painful days was 45.0 (38.7).
25% patients demonstrated improved cartilage thickness by at least 0.2 mm as against 15% who lost thickness at least by 0.01 mm.
55% patients showed improved Cell counts (below 500 microliters) in Synovial fluid.

DELAYED AND NONUNION:

Accelerates healing 90 % patients showed quick healing when used as a supplement with first surgery where high chance of avascular necrosis and Nonunion exist e.g.-# neck femur/ talus/distal tibia
Achieved union in 95% of cases in cases of Delayed union (when X-ray showed no callus in bridging construct or callus in stable construct in 3 -6 months)
Healing seen within 3 months in 80 % cases of atrophic non-union, failed implants of long bones after autologous bone marrow concentrate.
Cell therapy accelerated bone healing in the femur compared to in the tibia.

AVASCULAR NECROSIS OF HEAD FEMUR:

Significant reduction in pain in all the patients.
Back to work within 6 months after treatment.
Avoided the progression of the disease effectively in 90 % of hips with Stage I & II and in 40 % of hips with Stage III & IV disease.
10 % of hips with stage 1 and II progressed to Stage III: as compared to 50 % of Control patients progressing to Stage III.
6 % of Stage 1 and II of the hips needed Total Hip replacement.
60 % Stage III & IV hips needed Total Hip replacement.
Mean volume of necrotic lesion in Control group increased while volume was reduced in BM-MNC Group at 24 months.

The website contains no medical advice. All statements and opinions provided by the website are for educational and informational purposes. ||The treatment centres associated with Revita lifesciences provide surgical procedure only and are not involved in use or manufacture of any investigational drug ||Revita does not claim that any application or potential application, using autologous stem cells are approved by the FDA. We do not claim that these procedures work for any listed nor unlisted condition, intended or implied.||It’s important for potential patients to do their own research based on the options we present so that one can make an informed decision. Any decision to participate in experimental protocol is completely voluntary ||

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