Respiratory Disease

RESPIRATORY:

Many different conditions can cause severe limiting lung diseases:

Chronic obstructive pulmonary disease

Chronic obstructive pulmonary disease is a major inflammatory disease of the airways and an enormous therapeutic challenge. Within the spectrum of chronic obstructive pulmonary disease, pulmonary emphysema is characterized by the destruction of the alveolar walls with an increase in the air spaces distal to the terminal bronchioles but without significant pulmonary fibrosis.

Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease characterized by thickening and fibrosis of the alveolar walls. The etiology and pathogenesis are as yet unknown.

It is due to a response to some irritant, such as cigarette smoke, gastro-esophageal reflux, environmental pollution.

How it is done

Though the patho-physiology in both the diseases is different however the treatment protocol remains the same.

Stem cells administered intravenously accumulate in interstitial and cells administered via special nebulizer apparatus reach deep into alveoli. After intravenous infusion maximum no of cells reach lungs hence an effective therapeutic effect.

The cells provide Protection by differentiation of engrafted into specific and distinct lung cell phenotypes, and triggering production of growth factors which mobilizes endogenous stem cells and with a decrease in inflammatory cytokine. Protection from fibrosis also involves suppression of inflammation.

What to expect

In 80 % of Patients Respiratory and forced volume capacity increases significantly FVC > 60% diffuse lung capacity for carbon monoxide-DL_CO> 45% of the predicted values

Breathing improves over time. Oxygen saturation improves and dependence on oxygen reduces drastically Patients state that they feel they can once again “catch their breath.” Mucous secretion is reduced.

Expiratory parameters increases from 20% to 39% (nearly double) of the predicted values

FEV1/FVC ratio dropped from an average 45 % before the procedure to 28 % at 2 yr follow up. This decline occurred due to maintenance of the FEV1 and an increase in the FVC.

The website contains no medical advice. All statements and opinions provided by the website are for educational and informational purposes. ||The treatment centres associated with Revita lifesciences provide surgical procedure only and are not involved in use or manufacture of any investigational drug ||Revita does not claim that any application or potential application, using autologous stem cells are approved by the FDA. We do not claim that these procedures work for any listed nor unlisted condition, intended or implied.||It’s important for potential patients to do their own research based on the options we present so that one can make an informed decision. Any decision to participate in experimental protocol is completely voluntary ||

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