MALE INFERTILITY

Male Infertility

Male infertility /Azospermia

About 15% of couples are infertile with 1 in 3 cases being due to male infertility. Testes produce androgens and sperms. Spermatogonial stem cells differentiate into mature spermatozoa in seminiferous tubules of testes.

Bone marrow and adipose derived stem cells have potential capabilities to replenish germ cells, supporting cells and testosterone producing cells hence when injected into seminiferous tubules or interstitial spaces are  able to transdifferentiate into germ cells (spermatogonia and spermatocytes)  and Sertoli and Leydig as well.

Bone marrow and adipose derived stem cells have potential capabilities to replenish germ cells, supporting cells and testosterone producing cells hence when injected into seminiferous tubules or interstitial spaces are  able to transdifferentiate into germ cells (spermatogonia and spermatocytes)  and Sertoli and Leydig as well.

How it is done

Patients are evaluated for serum levels of gonadotrophins, testosterone and prolactin
infectious genital disease, and anatomical abnormalities of the genital tract as these issues if present need to be corrected first.
Patients advised to strictly avoid smoking, drug or alcohol consumption

As a day care procedure 120 ml of Bone marrow and 200 ml of fat is aspirated and processed in a closed system for stem cells isolation. 2 ml volume having at least 2million stem cells per kg body weight is injected either into

 

 *Intratesticular  

 * Into the feeding artery of testis

What to expect

Appearance of normal healthy sperm cells at semen analysis is seen by 6 months in 60 %.

*These sperms have Normal activity and possess ability to fertilise ova (validated in lab)

* Fine needle aspiration (FNA) cytology reveals evidence of differentiation and Normal intra testicular spermatogenesis

*80 % Patients with oligospermia report significant increase (10 to 20 times) in sperm counts after 3 months of stem cell application

The website contains no medical advice. All statements and opinions provided by the website are for educational and informational purposes. ||The treatment centres associated with Revita lifesciences provide surgical procedure only and are not involved in use or manufacture of any investigational drug ||Revita does not claim that any application or potential application, using autologous stem cells are approved by the FDA. We do not claim that these procedures work for any listed nor unlisted condition, intended or implied.||It’s important for potential patients to do their own research based on the options we present so that one can make an informed decision. Any decision to participate in experimental protocol is completely voluntary ||

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