Revita Life Sciences

Female Infertility

There are many biological causes (polycystic ovary//anovulatory//endometrial insufficiency) of infertility, including some that medical intervention can treat. Situations exist where multiple IVF have not worked, for reasons that cannot be elucidated by even the most sophisticated diagnostic methods and testing.

1.  Anovulatory: lack of ova production can be primary or secondary to diseases like polycystic ovary etc

Ovarian rejuvenation & stimulation via transvaginal administration of stem cells makes the local microenvironment in ovaries favourable thus helps in production of healthy and functional ova.

2. Endometrial causes: leading to infertility are either nonspecific or secondary to diseases like Asherman syndrome, tuberculosis multiple abortions, D&C etc.

MSCs tend to secrete antifibrotic, angiogenic, antiapoptotic, immune suppressive factors in a paracrine manner which promote the regeneration of the endometrial lining of the uterus.

Stem cell application improves endometrial microenvironment (Endometrial rejuvenation) hence  contributing towards promoting fertility and pregnancy in women especially in Patients with poor endometrial growth despite hormonal treatment.

How It Is Done

Patients are evaluated for hormone levels, infectious genital disease, anatomical abnormalities of the genital tract as these issues if present need to be corrected first.
Patients advised to strictly avoid smoking, drug or alcohol consumption and have a positive life style.

As a day care procedure 240 ml of Bone marrow and 100 ml of fat is aspirated and processed for stem cell isolation. 2 ml of stem cells processed is injected either  

  • Transvaginal administration of cells in ovaries
  • Into the feeding artery of ovaries and uterus
  • In the Endometrium of uterus
  • Along with multiple flushing of platelet rich plasma in the uterine wall

What To Expect

55 percent of women have shown evidence of live pregnancy within 6 to 9 months after undergoing the complete treatment protocol.

The endometrium  grows up to 7 mm.

Pregnancy is achieved with embryo transfer in 50% of cases .

 90% of  patients experienced regular menstruation after the stem cell application