Female Infertility
Female infertility
There are many biological causes (polycystic ovary//anovulatory//endometrial insufficiency) of infertility, including some that medical intervention can treat. Situations exist where multiple IVF have not worked, for reasons that cannot be elucidated by even the most sophisticated diagnostic methods and testing.
1. Anovulatory: lack of ova production can be primary or secondary to diseases like polycystic ovary etc
Ovarian rejuvenation & stimulation via transvaginal administration of stem cells makes the local microenvironment in ovaries favourable thus helps in production of healthy and functional ova.
2. Endometrial causes: leading to infertility are either nonspecific or secondary to diseases like Asherman syndrome, tuberculosis multiple abortions, D&C etc
MSCs tend to secrete antifibrotic, angiogenic, antiapoptotic, immune suppressive factors in a paracrine manner which promote the regeneration of the endometrial lining of the uterus
Stem cell application improves endometrial microenvironment (Endometrial rejuvenation) hence contributing towards promoting fertility and pregnancy in women esp. in Patients with poor endometrial growth despite hormonal treatment.
1. Anovulatory: lack of ova production can be primary or secondary to diseases like polycystic ovary etc
Ovarian rejuvenation & stimulation via transvaginal administration of stem cells makes the local microenvironment in ovaries favourable thus helps in production of healthy and functional ova.
2. Endometrial causes: leading to infertility are either nonspecific or secondary to diseases like Asherman syndrome, tuberculosis multiple abortions, D&C etc
MSCs tend to secrete antifibrotic, angiogenic, antiapoptotic, immune suppressive factors in a paracrine manner which promote the regeneration of the endometrial lining of the uterus
Stem cell application improves endometrial microenvironment (Endometrial rejuvenation) hence contributing towards promoting fertility and pregnancy in women esp. in Patients with poor endometrial growth despite hormonal treatment.
How it is done
Patients are evaluated for hormone levels, infectious genital disease, anatomical abnormalities of the genital tract as these issues if present need to be corrected first.
Patients advised to strictly avoid smoking, drug or alcohol consumption and have a positive life style
As a day care procedure 240 ml of Bone marrow and 100 ml of fat is aspirated and processed for stem cells isolation. 2 ml of stem cells processed is injected either
* Trans vaginal administration of cells in ovaries
* Into the feeding artery of ovaries and uterus
* in the Endometrium of uterus
*along with multiple flushing of platelet rich plasma in the uterine wall
What to expect
55 percent of women have shown evidence of live pregnancy within 6 to 9 months after undergoing the complete treatment protocol.
The endometrium grows up to 7 mm.
Pregnancy is achieved with embryo transfer in 50 % of cases .
90 % of patients experienced regular menstruation after the stem cell application
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2 nd Floor Hb, Specialty Hospital & Research Institute, Near Bhoorarani Gate,
Kashipur Road, Rudrapur,
Udham Singh Nagar, Uttarakhand,
India 263153
- +915944240234, +919897080188
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